Sinopsis

After witnessing a small plane crash, Kimble rescues the pilot and two passengers, senatorial candidate Glenn Madison, and his assistant/secret lover, Pat Haynes. Glenn’s PR man, Russ Haynes (Pat’s husband) arranges for a sketch artist to draw a portrait of Glenn’s rescuer whom had left the scene. Russ locates the fugitive and brings him to the Madison estate for Glenn to congratulate him for saving his life. But the sketch artist recognizes Kimble and calls the police whom arrives at the mansion. But Russ and Glenn hold them off. Meanwhile, Glenn’s wife, Claire, recognizes Kimble, and threatens to turn him in unless he tells her of the person that Glenn has seeing, aware of her husband’s long history of infidelity. But Kimble claims not to know anything. When Kimble confronts Pat, she admits to her affair with Glenn. Claire overhears the conversation and decides to destroy her husband’s image. But Glenn murders her and then calls the police again to put the blame of the fugitive.

Richard Kimble is falsely convicted of his wife’s murder and given the death penalty. En route to death row, Kimble’s train derails and crashes, allowing him to escape and begin a cross-country search for the real killer, a “one-armed man”. At the same time, Dr. Kimble is hounded by the authorities, most notably dogged by Police Lieutenant Philip Gerard.